2000–2010

• Jill-Lyn Euto, an 18 year old student, was found stabbed to death in her sixth-floor apartment at 600 James St, Syracuse, NY on 28 January 2001. No arrests have been made.^[47]
• Evelyn Hernandez, and her 5-year-old son Alex, last heard from on 1 May 2002 at her residence in San Francisco, California. Her wallet was found several days later, in South San Francisco. Hernandez was nine months pregnant at the time and on 24 July 2002 her torso was found floating in San Francisco Bay. Her unborn child and her son Alex have not been found. The case was profiled twice on America's Most Wanted during the summer of 2003.^[48]
• Rashawn Brazell, disappeared after leaving his home in Bushwick, Brooklyn, New York, United States, on the morning of 14 February 2005. His dismembered body parts were later found in garbage bags. America's Most Wanted profiled the case three times, on 29 September 2005; 1 April 2006; and 9 December 2006.^[49][50]
• Gail DeLay, age 49, was murdered sometime between July 23 and 24, 2005, in her Dallas, TX, apartment. She was found on the morning of Sunday, July 24 by a friend. She had been severely beaten. Delay was a freelance artist, illustrator, and motivational speaker and had been a volunteer with the SPCA for 18 years. Dallas police investigated and quickly ran out of leads.^{[51][52][52][53]}
• Robert Wone, age 32, was murdered on August 2, 2006, in his friend's Washington, D.C., apartment. He was "restrained, incapacitated, and sexually assaulted" prior to his death. The only individuals present in the apartment at the time were its three residents, all friends of Wone. They have denied involvement and insisted that an intruder committed the crime. Authorities claim that there was no evidence of a break-in, the apartment appeared to be washed cleaned, the three residents appeared freshly showered, and the evidence was not consistent with the residents' accounts. In addition, the residents tampered with the crime scene, waited an inordinate amount of time to call 911, and exhibited strange behavior when paramedics and police arrived. Authorities believe that either some or all of the three house-mates murdered Wone and engaged in a cover-up.^[54][55]
• Lane Bryant shooting – on February 2, 2008, a gunman trying to rob a Lane Bryant store killed five women (a manager and four customers). The shooter has not been apprehended, although police do not consider it a "cold case" yet.